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This study aimed to investigate whether melatonin supplementation can improve IVF outcomes in women of advanced maternal age by modulating cuproptosis and ferroptosis

Moreover, supplements may react when taken in higher doses without gradual introduction

Lancet Neurol 18:724735 Silva C, Pinto M, Fernandes C, Benfeito S, Borges F (2021) Antioxidant therapy and neurodegenerative disorders: lessons from clinical trials

naturally small molecular reducing agents will never be as specific as the substrate-specific enzymes of the well-controlled antioxidant machinery of the cell, however with a finely tuned and designed thiolate basicity the redox potential and therefore the selectivity of the antioxidant thiol can be confined to a narrower range